Ontology highlight
ABSTRACT:
SUBMITTER: Parikh VN
PROVIDER: S-EPMC4610144 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Parikh Victoria N VN Park Joseph J Nikolic Ivana I Channick Richard R Yu Paul B PB De Marco Teresa T Hsue Priscilla Y PY Chan Stephen Y SY
Journal of acquired immune deficiency syndromes (1999) 20151101 3
Dysregulation of microRNA-21 (miR-21) is independently associated with HIV infection, pulmonary arterial hypertension (PAH), and hepatitis C virus (HCV) infection. To assess the expression of miR-21 in these overlapping comorbidities, we measured plasma miR-21 in HIV with and without PAH and then stratified by concomitant HCV infection. MiR-21 was increased in HIV and HIV-PAH versus uninfected subjects, but it did not differ between these groups. HIV/HCV coinfection correlated with even higher m ...[more]