Ontology highlight
ABSTRACT:
SUBMITTER: Ma Y
PROVIDER: S-EPMC4610970 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Ma Yiyangzi Y Shi Na N Li Mengtao M Chen Fei F Niu Haitao H
Genomics, proteomics & bioinformatics 20150801 4
Systemic autoimmune diseases are a group of heterogeneous disorders caused by both genetic and environmental factors. Although numerous causal genes have been identified by genome-wide association studies (GWAS), these susceptibility genes are correlated to a relatively low disease risk, indicating that environmental factors also play an important role in the pathogenesis of disease. The intestinal microbiome, as the main symbiotic ecosystem between the host and host-associated microorganisms, h ...[more]