Previous miscarriage and the subsequent risk of preterm birth in Scotland, 1980-2008: a historical cohort study.

ABSTRACT:

Objective

To determine whether the relationship between previous miscarriage and risk of preterm birth changed over the period 1980-2008, and to determine whether the pattern varied according to the cause of the preterm birth.

Design

Linked birth databases.

Setting

All Scottish NHS hospitals.

Population

A total of 732 719 nulliparous women with a first live birth between 1980 and 2008.

Methods

Risk was estimated using logistic regression.

Main outcome measures

Preterm birth, subdivided by cause (spontaneous, induced with a diagnosis of pre-eclampsia, or induced without a diagnosis of pre-eclampsia) and severity [extreme (24-28 weeks of gestation), moderate (29-32 weeks of gestation), and mild (33-36 weeks of gestation)].

Results

Consistent

SUBMITTER: Oliver-Williams C 

PROVIDER: S-EPMC4611958 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature