Ontology highlight
ABSTRACT:
SUBMITTER: Rubicz R
PROVIDER: S-EPMC4613484 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Rubicz Rohina R Yolken Robert R Drigalenko Eugene E Carless Melanie A MA Dyer Thomas D TD Kent Jack J Curran Joanne E JE Johnson Matthew P MP Cole Shelley A SA Fowler Sharon P SP Arya Rector R Puppala Sobha S Almasy Laura L Moses Eric K EK Kraig Ellen E Duggirala Ravindranath R Blangero John J Leach Charles T CT Göring Harald H H HH
European journal of human genetics : EJHG 20150311 11
Populations and individuals differ in susceptibility to infections because of a number of factors, including host genetic variation. We previously demonstrated that differences in antibody titer, which reflect infection history, are significantly heritable. Here we attempt to identify the genetic factors influencing variation in these serological phenotypes. Blood samples from >1300 Mexican Americans were quantified for IgG antibody level against 12 common infections, selected on the basis of th ...[more]