Ontology highlight
ABSTRACT:
SUBMITTER: Midgett M
PROVIDER: S-EPMC4614502 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Midgett Madeline M Chivukula Venkat Keshav VK Dorn Calder C Wallace Samantha S Rugonyi Sandra S
Journal of the Royal Society, Interface 20151001 111
Blood flow is inherently linked to embryonic cardiac development, as haemodynamic forces exerted by flow stimulate mechanotransduction mechanisms that modulate cardiac growth and remodelling. This study evaluated blood flow in the embryonic heart outflow tract (OFT) during normal development at each stage between HH13 and HH18 in chicken embryos, in order to characterize changes in haemodynamic conditions during critical cardiac looping transformations. Two-dimensional optical coherence tomograp ...[more]