Ontology highlight
ABSTRACT:
SUBMITTER: Wild K
PROVIDER: S-EPMC4615810 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Wild Klemens K Sinning Irmgard I
RNA biology 20140101 11
More than one third of the cellular proteome is destined for incorporation into cell membranes or export from the cell. In all domains of life, the signal recognition particle (SRP) delivers these proteins to the membrane and protein traffic falls apart without SRP logistics. With the aid of a topogenic transport signal, SRP retrieves its cargo right at the ribosome, from where they are sorted to the translocation channel. Mammalian SRP is a ribonucleoprotein complex consisting of an SRP RNA of ...[more]