Ontology highlight
ABSTRACT:
SUBMITTER: Modiano JF
PROVIDER: S-EPMC4618101 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Modiano Jaime F JF Lindborg Beth A BA McElmurry Ron T RT Lewellen Mitzi M Forster Colleen L CL Zamora Edward A EA Schaack Jerome J Bellgrau Donald D O'Brien Timothy D TD Tolar Jakub J
Cancer immunology, immunotherapy : CII 20150807 11
The potential of mesenchymal stromal cells (MSCs) to inhibit anti-tumor immunity is becoming increasingly well recognized, but the precise steps affected by these cells during the development of an anti-tumor immune response remain incompletely understood. Here, we examined how MSCs affect the steps required to mount an effective anti-tumor immune response following administration of adenovirus Fas ligand (Ad-FasL) in the Lewis lung carcinoma (LL3) model. Administration of bone marrow-derived MS ...[more]