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Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae: The First Reported Case in South Korea.

ABSTRACT: This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ethambutol, and rifampin. To the best of our knowledge, this is the first confirmed case of a lung disease caused by M. simiae in South Korea.

SUBMITTER: Jeong SH

PROVIDER: S-EPMC4620346 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium simiae: The First Reported Case in South Korea.

Jeong Suk Hyeon SH Kim Su-Young SY Lee Hyun H Ham Jun Soo JS Hwang Keum Bit KB Hwang Subin S Shin Sun Hye SH Chung Myung Jin MJ Lee Seung Heon SH Shin Sung Jae SJ Koh Won-Jung WJ

Tuberculosis and respiratory diseases 20151001 4

This is a report of the first South Korean case of a lung disease caused by Mycobacterium simiae. The patient was a previously healthy 52-year-old female. All serial isolates were identified as M. simiae by multi-locus sequencing analysis, based on hsp65, rpoB, 16S-23S rRNA internal transcribed spacer, and 16S rRNA fragments. A chest radiography revealed deterioration, and the follow-up sputum cultures were persistently positive, despite combination antibiotic treatment, including azithromycin, ...[more]

PMID: 26508940

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