Ontology highlight
ABSTRACT:
SUBMITTER: Wang YF
PROVIDER: S-EPMC4621603 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Wang Ya-Feng YF Han Yue Y Zhang Rui R Qin Li L Wang Ming-Xu MX Ma Le L
Scientific reports 20151027
Three high-density lipoprotein (HDL)-related loci have been reported to be associated with age-related macular degeneration (AMD), but the results were inconsistent. In this study, the cholesteryl ester transfer protein (CETP) rs3764261 variant was significantly associated with an increased risk of AMD (odds ratio [OR] = 1.13, 95% confidence interval [CI]: 1.05-1.21, P < 0.001), and the hepatic lipase (LIPC) rs10468017 variant was associated with a significantly decreased risk of AMD (OR = 0.81, ...[more]