Ontology highlight
ABSTRACT:
SUBMITTER: Cho H
PROVIDER: S-EPMC4622078 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Cho Hansang H Seo Ji Hae JH Wong Keith H K KH Terasaki Yasukazu Y Park Joseph J Bong Kiwan K Arai Ken K Lo Eng H EH Irimia Daniel D
Scientific reports 20151027
Blood-brain barrier (BBB) pathology leads to neurovascular disorders and is an important target for therapies. However, the study of BBB pathology is difficult in the absence of models that are simple and relevant. In vivo animal models are highly relevant, however they are hampered by complex, multi-cellular interactions that are difficult to decouple. In vitro models of BBB are simpler, however they have limited functionality and relevance to disease processes. To address these limitations, we ...[more]