Ontology highlight
ABSTRACT:
SUBMITTER: Delmar JA
PROVIDER: S-EPMC4622206 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20150824 11
It is widely accepted that the increased use of antibiotics has resulted in bacteria with developed resistance to such treatments. These organisms are capable of forming multi-protein structures that bridge both the inner and outer membrane to expel diverse toxic compounds directly from the cell. Proteins of the resistance nodulation cell division (RND) superfamily typically assemble as tripartite efflux pumps, composed of an inner membrane transporter, a periplasmic membrane fusion protein, and ...[more]