Ontology highlight
ABSTRACT:
SUBMITTER: Young K
PROVIDER: S-EPMC4622287 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Young Kate K Smyth Elizabeth E Chau Ian I
Therapeutic advances in gastroenterology 20151101 6
Ramucirumab, a fully humanized monoclonal antibody directed against vascular endothelial growth factor receptor 2, is the first targeted agent to have demonstrated an improvement in survival, as a single agent or in combination, in a molecularly unselected population in gastro-oesophageal cancer. Now that second-line treatment is routinely considered for patients with advanced gastro-oesophageal cancer, ramucirumab, with its favourable toxicity profile compared with cytotoxic treatment, provides ...[more]