Evaluating immune responses after sipuleucel-T therapy.
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ABSTRACT:
SUBMITTER: Strauss J
PROVIDER: S-EPMC4622939 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Evaluating immune responses after sipuleucel-T therapy.
Strauss Julius J Madan Ravi A RA Figg William D WD
Cancer biology & therapy 20150608 8
Following FDA approval of sipuleucel-T in 2010 for metastatic castration resistant prostate cancer (mCRPC), several studies have described the effect of sipuleucel-T on peripheral immune responses. Retrospective associations have also been made with immune responses and survival. A recently published study by Fong et al. was the first to characterize the immune response of sipuleucel-T in the tumor microenvironment. The findings of this study have been hypothesis generating, yet it remains uncle ...[more]
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