Ontology highlight
ABSTRACT:
SUBMITTER: Lin ZL
PROVIDER: S-EPMC4623140 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Lin Zi Li ZL Cui Xiang-Shun XS Namgoong Suk S Kim Nam-Hyung NH
The Journal of reproduction and development 20150606 5
Junction-mediating and regulatory protein (JMY) is a regulator of both transcription and actin filament assembly. JMY is a critical nucleation-promoting factor (NPF); however, its role in the development of mammalian embryos is poorly understood. In the current study, we investigated the functional roles of the NPF JMY in porcine embryos. Porcine embryos expressed JMY mRNA and protein, and JMY protein moved from the cytoplasm to the nucleus at later embryonic developmental stages. Knockdown of J ...[more]