Project description:The author's contribution up to 1990 was reviewed in part I and the echo contributions from 1991 to 2020 will be reviewed in part II. These include defining the relationship between the quantity of shunt across the atrial septal defect (ASD) and the diameter of ASD by echo and angio on the one side and the stretched diameter of the ASD on the other; echocardiographic assessment of balloon-stretched diameter of secundum ASDs; development of echocardiographic predictors of accomplishment of percutaneous closure of ASDs with the buttoned device, highlighting limitations of echocardiography in comprehensive assessment of mixed type of total anomalous pulmonary venous connection; description of follow-up echocardiographic results of transcatheter closure of ASD with buttoned device; review of ultrasound studies; depiction of collaborative echocardiographic and Doppler studies; echocardiographic appraisal of the outcome of balloon pulmonary valvuloplasty; editorials; ventricular septal aneurysm causing pulmonary outflow tract obstruction in the morphologic left ventricle in corrected transposition of the great arteries; dependability of echocardiographic assessment of angiographic minimal diameter of the ductus; occurrence of supravalvular pulmonary artery stenosis after a Nuss procedure; echocardiographic assessment of neonates who were suspected of having heart disease; role of echocardiographic studies in the appraisal of patent ductus arteriosus in the premature babies; and the role of pressure recovery in explaining differences between simultaneously measured Doppler and cardiac catheterization pressure gradients across outflow tract stenotic lesions.

| S-EPMC7230637 | biostudies-literature

Concerns regarding risk factors for SARS-CoV-2 transmission to pets: author's reply.

Project description: Not available

| S-EPMC10077841 | biostudies-literature

Author's View: a nuclear transcription factor relocalizing to mitochondria rescues cells from proteotoxic aggregates.

Project description:Mitochondrial proteostasis is essential for survival, and imbalances can result in severe human diseases. We identified a novel stress response triggered upon accumulation of proteotoxic aggregates in the mitochondrial matrix. Mitochondria-to-nucleus signaling results in a transcriptional response and translocation of a nuclear transcription factor into mitochondria to maintain mitochondrial gene expression.

| S-EPMC6961659 | biostudies-literature

Author's view: radiation and immunotherapy as systemic therapy for solid tumors.

Project description:The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.

| S-EPMC4404906 | biostudies-other

A step-by-step guide to mastering retrograde coronary chronic total occlusion intervention in 2018: The author's perspective.

Project description:Chronic total occlusion remains one of the most challenging subsets and represents the "last frontier" of percutaneous coronary intervention. Retrograde recanalization is one of the most significant amendments of the technique and has become an important complement to the classical antegrade approach. It yields a high success rate even in most complex patients. With emergence of important iterations, this approach has become safer, faster, and more successful. The author proposes a step-by-step guide to the retrograde approach with alternatives to various steps for operators wishing to embark on this strategy.

| S-EPMC6310897 | biostudies-literature

E-GTEX-8

Project description:The Genotype-Tissue Expression (GTEx) project v8

2024-02-24 | E-GTEX-8 | ExpressionAtlas

E-GEUV-1

Project description:RNA-sequencing of 465 lymphoblastoid cell lines from the 1000 Genomes

2019-07-15 | E-GEUV-1 | ExpressionAtlas