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Neural mechanisms supporting maladaptive food choices in anorexia nervosa.


ABSTRACT: People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day.

SUBMITTER: Foerde K 

PROVIDER: S-EPMC4624561 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Neural mechanisms supporting maladaptive food choices in anorexia nervosa.

Foerde Karin K   Steinglass Joanna E JE   Shohamy Daphna D   Walsh B Timothy BT  

Nature neuroscience 20151012 11


People routinely make poor choices, despite knowledge of negative consequences. The authors found that individuals with anorexia nervosa, who make maladaptive food choices to the point of starvation, engaged the dorsal striatum more than healthy controls when making choices about what to eat, and that activity in fronto-striatal circuits was correlated with their actual food consumption in a meal the next day. ...[more]

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