Ontology highlight
ABSTRACT:
SUBMITTER: Bhin J
PROVIDER: S-EPMC4625071 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Bhin Jinhyuk J Jeong Hoe-Su HS Kim Jong Soo JS Shin Jeong Oh JO Hong Ki Sung KS Jung Han-Sung HS Kim Changhoon C Hwang Daehee D Kim Kye-Seong KS
Molecules and cells 20151007 10
Non-coding microRNAs (miRNAs) regulate the translation of target messenger RNAs (mRNAs) involved in the growth and development of a variety of cells, including primordial germ cells (PGCs) which play an essential role in germ cell development. However, the target mRNAs and the regulatory networks influenced by miRNAs in PGCs remain unclear. Here, we demonstrate a novel miRNAs control PGC development through targeting mRNAs involved in various cellular pathways. We reveal the PGC-enriched express ...[more]