A positive-negative mode of population covariation links brain connectivity, demographics and behavior.

ABSTRACT: We investigated the relationship between individual subjects' functional connectomes and 280 behavioral and demographic measures in a single holistic multivariate analysis relating imaging to non-imaging data from 461 subjects in the Human Connectome Project. We identified one strong mode of population co-variation: subjects were predominantly spread along a single 'positive-negative' axis linking lifestyle, demographic and psychometric measures to each other and to a specific pattern of brain connectivity.

SUBMITTER: Smith SM 

PROVIDER: S-EPMC4625579 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature