Ontology highlight
ABSTRACT:
SUBMITTER: Rao F
PROVIDER: S-EPMC4627078 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Rao Feng F Short Francesca L FL Voss Jarrod E JE Blower Tim R TR Orme Anastasia L AL Whittaker Tom E TE Luisi Ben F BF Salmond George P C GP
Nucleic acids research 20150908 19
Genes encoding toxin-antitoxin (TA) systems are near ubiquitous in bacterial genomes and they play key roles in important aspects of bacterial physiology, including genomic stability, formation of persister cells under antibiotic stress, and resistance to phage infection. The CptIN locus from Eubacterium rectale is a member of the recently-discovered Type III class of TA systems, defined by a protein toxin suppressed by direct interaction with a structured RNA antitoxin. Here, we present the cry ...[more]