Ontology highlight
ABSTRACT:
SUBMITTER: Geiger TL
PROVIDER: S-EPMC4628787 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Geiger Terrence L TL Rubnitz Jeffrey E JE
Discovery medicine 20150401 105
Acute myeloid leukemia (AML) is a set of related diseases characterized by the immortalization and uncontrolled expansion of myeloid precursor cells. Core therapy for AML has remained unchanged for nearly 30 years, and survival rates remain unsatisfactory. However, advances in the immunotherapy of AML have created opportunities for improved outcomes. Enforcing a tumor-specific immune response through the re-direction of the adaptive immune system, which links remarkable specificity with potent c ...[more]