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Platelets in the pathogenesis of acute respiratory distress syndrome.

ABSTRACT: Platelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution of lung injury.

SUBMITTER: Yadav H

PROVIDER: S-EPMC4628982 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Platelets in the pathogenesis of acute respiratory distress syndrome.

Yadav Hemang H Kor Daryl J DJ

American journal of physiology. Lung cellular and molecular physiology 20150828 9

Platelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution ...[more]

PMID: 26320157

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