Ontology highlight
ABSTRACT: Objective
The purpose of this study was to identify clusters of diagnoses in elderly patients with multimorbidity, attended in primary care.Design
Cross-sectional study.Setting
251 primary care centres in Catalonia, Spain.Participants
Individuals older than 64 years registered with participating practices.Main outcome measures
Multimorbidity, defined as the coexistence of 2 or more ICD-10 disease categories in the electronic health record. Using hierarchical cluster analysis, multimorbidity clusters were identified by sex and age group (65-79 and ≥80 years).Results
322,328 patients with multimorbidity were included in the analysis (mean age, 75.4 years [Standard deviation, SD: 7.4], 57.4% women; mean of 7.9 diagnoses [SD: 3.9]). For both men and women, the first cluster in both age groups included the same two diagnoses: Hypertensive diseases and Metabolic disorders. The second cluster contained three diagnoses of the musculoskeletal system in the 65- to 79-year-old group, and five diseases coincided in the ≥80 age group: varicose veins of the lower limbs, senile cataract, dorsalgia, functional intestinal disorders and shoulder lesions. The greatest overlap (54.5%) between the three most common diagnoses was observed in women aged 65-79 years.Conclusion
This cluster analysis of elderly primary care patients with multimorbidity, revealed a single cluster of circulatory-metabolic diseases that were the most prevalent in both age groups and sex, and a cluster of second-most prevalent diagnoses that included musculoskeletal diseases. Clusters unknown to date have been identified. The clusters identified should be considered when developing clinical guidance for this population.
SUBMITTER: Foguet-Boreu Q
PROVIDER: S-EPMC4629893 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature

PloS one 20151102 11
<h4>Objective</h4>The purpose of this study was to identify clusters of diagnoses in elderly patients with multimorbidity, attended in primary care.<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>251 primary care centres in Catalonia, Spain.<h4>Participants</h4>Individuals older than 64 years registered with participating practices.<h4>Main outcome measures</h4>Multimorbidity, defined as the coexistence of 2 or more ICD-10 disease categories in the electronic health record. Using hierarchic ...[more]