Ontology highlight
ABSTRACT:
SUBMITTER: Nasser HM
PROVIDER: S-EPMC4630296 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Nasser Helen M HM Chen Yu-Wei YW Fiscella Kimberly K Calu Donna J DJ
Frontiers in behavioral neuroscience 20151103
Sign-tracking rats show heightened sensitivity to food- and drug-associated cues, which serve as strong incentives for driving reward seeking. We hypothesized that this enhanced incentive drive is accompanied by an inflexibility when incentive value changes. To examine this we tested rats in Pavlovian outcome devaluation or second-order conditioning prior to the assessment of sign-tracking tendency. To assess behavioral flexibility we trained rats to associate a light with a food outcome. After ...[more]