Pneumococcal carbohydrate transport: food for thought.
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ABSTRACT:
SUBMITTER: Buckwalter CM
PROVIDER: S-EPMC4630977 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Publications
Pneumococcal carbohydrate transport: food for thought.
Buckwalter Carolyn M CM King Samantha J SJ
Trends in microbiology 20120905 11
Streptococcus pneumoniae relies exclusively on carbohydrates as a carbon source and devotes 30% of all transport mechanisms to carbohydrate import. Pneumococci utilize at least 32 carbohydrates in vitro. However, some proposed substrates are not human-derived, so it is unclear where they are encountered in the host niche, and other substrates remain unidentified. The majority of transporter loci are conserved, arguing against redundancy and instead for distinct roles during pathogenesis. Despite ...[more]
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