Ontology highlight
ABSTRACT:
SUBMITTER: Chen Y
PROVIDER: S-EPMC4632927 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Chen Yuan Y Wang Guojin G Zhang Peng P Liu Yimei Y Yao Yuanyuan Y Wang Hai H Wang Yuanguo Y
Thoracic cancer 20150409 6
<h4>Background</h4>To study the relationship between loss of heterozygosity (LOH) at the human leukocyte antigen (HLA) locus and the pathogenicity and clinicopathological features of thymic epithelial tumors (TET).<h4>Methods</h4>Tumor and adjacent normal tissues were isolated from 36 TET patients. Five microsatellite loci (D6S1666, D6S265, D6S273, DS6276, and D6S291) within the HLA locus were amplified by polymerase chain reaction. DNA sequencing was used to measure the frequency of microsatell ...[more]