Ontology highlight
ABSTRACT:
SUBMITTER: Murakami Y
PROVIDER: S-EPMC4633735 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Murakami Yoshiki Y Kubo Shoji S Tamori Akihiro A Itami Saori S Kawamura Etsushi E Iwaisako Keiko K Ikeda Kazuo K Kawada Norifumi N Ochiya Takahiro T Taguchi Y-h YH
Scientific reports 20151105
Intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC) are liver originated malignant tumors. Of the two, ICC has the worse prognosis because it has no reliable diagnostic markers and its carcinogenic mechanism is not fully understood. The aim of this study was to integrate metabolomics and transcriptomics datasets to identify variances if any in the carcinogenic mechanism of ICC and HCC. Ten ICC and 6 HCC who were resected surgically, were enrolled. miRNA and mRNA expression a ...[more]