Ontology highlight
ABSTRACT:
SUBMITTER: Stastna JJ
PROVIDER: S-EPMC4634109 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Stastna Jana J JJ Snoek L Basten LB Kammenga Jan E JE Harvey Simon C SC
Scientific reports 20151105
Dietary restriction appears to act as a general non-genetic mechanism that can robustly prolong lifespan. There have however been reports in many systems of cases where restricted food intake either shortens, or does not affect, lifespan. Here we analyze lifespan and the effect of food restriction via deprived peptone levels on lifespan in wild isolates and introgression lines (ILs) of the nematode Caenorhabditis elegans. These analyses identify genetic variation in lifespan, in the effect of th ...[more]