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ABSTRACT: Background
The purpose of this study was to investigate the prognostic significance of early (30-day) hospital readmission (EHR) on mortality after pancreatectomy.Methods
Using a prospectively collected institutional database linked with a statewide dataset, we evaluated the association between EHR and overall mortality in all patients undergoing pancreatectomy at our tertiary institution (2005 to 2010).Results
Of 595 pancreatectomy patients, EHR occurred in 21.5%. Overall mortality was 29.4% (median follow-up 22.7 months). Patients with EHR had decreased survival compared with those who were not readmitted (P = .011). On multivariate analysis adjusting for baseline group differences, EHR for gastrointestinal-related complications was a significant independent predictor of mortality (hazard ratio 2.30, P = .001).Conclusions
In addition to known risk factors, 30-day readmission for gastrointestinal-related complications following pancreatectomy independently predicts increased mortality. Additional studies are necessary to identify surgical, medical, and social factors contributing to EHR, as well as interventions aimed at decreasing postpancreatectomy morbidity and mortality.
SUBMITTER: Hicks CW
PROVIDER: S-EPMC4634566 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hicks Caitlin W CW Tosoian Jeffrey J JJ Craig-Schapiro Rebecca R Valero Vicente V Cameron John L JL Eckhauser Frederic E FE Hirose Kenzo K Makary Martin A MA Pawlik Timothy M TM Ahuja Nita N Weiss Matthew J MJ Wolfgang Christopher L CL
American journal of surgery 20150629 4
<h4>Background</h4>The purpose of this study was to investigate the prognostic significance of early (30-day) hospital readmission (EHR) on mortality after pancreatectomy.<h4>Methods</h4>Using a prospectively collected institutional database linked with a statewide dataset, we evaluated the association between EHR and overall mortality in all patients undergoing pancreatectomy at our tertiary institution (2005 to 2010).<h4>Results</h4>Of 595 pancreatectomy patients, EHR occurred in 21.5%. Overal ...[more]