Ontology highlight
ABSTRACT:
SUBMITTER: Bogaert L
PROVIDER: S-EPMC4635499 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Bogaert Lies L Woodham Andrew W AW Da Silva Diane M DM Martens Ann A Meyer Evelyne E Kast W Martin WM
The Journal of general virology 20150604 9
Equine sarcoids are highly recurrent bovine papillomavirus (BPV)-induced fibroblastic neoplasms that are the most common skin tumours in horses. In order to facilitate the study of potential equine sarcoid prophylactics or therapeutics, which can be a slow and costly process in equines, a murine model for BPV-1 protein-expressing equine sarcoid-like tumours was developed in mice through stable transfection of BPV-1 E5 and E6 in a murine fibroblast tumour cell line (K-BALB). Like equine sarcoids, ...[more]