Unknown

Dataset Information

0

Patent Foramen Ovale and Stroke-Current Status.


ABSTRACT: Patent foramen ovale (PFO) is growing in clinical interest because of a renewed focus on embolic stroke of undetermined source (ESUS), the PFO attributable fraction (the 10-point Risk of Paradoxical Embolism score), technical advances in PFO diagnosis, and the emergence of endovascular device closure as a treatment option. However, recent randomized controlled trials of the management of patients with ESUS and PFO failed to demonstrate the superiority of closure over medical treatment. The mechanisms of stroke other than paradoxical embolism may be important in patients with ESUS and PFO. This paper reviews the current understanding of the pathophysiology of stroke and therapeutic options in patients with PFO and ESUS.

SUBMITTER: Bang OY 

PROVIDER: S-EPMC4635723 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Patent Foramen Ovale and Stroke-Current Status.

Bang Oh Young OY   Lee Mi Ji MJ   Ryoo Sookyung S   Kim Suk Jae SJ   Kim Ji Won JW  

Journal of stroke 20150930 3


Patent foramen ovale (PFO) is growing in clinical interest because of a renewed focus on embolic stroke of undetermined source (ESUS), the PFO attributable fraction (the 10-point Risk of Paradoxical Embolism score), technical advances in PFO diagnosis, and the emergence of endovascular device closure as a treatment option. However, recent randomized controlled trials of the management of patients with ESUS and PFO failed to demonstrate the superiority of closure over medical treatment. The mecha  ...[more]

Similar Datasets

| S-EPMC6083869 | biostudies-literature
| S-EPMC10574307 | biostudies-literature
| S-EPMC8828961 | biostudies-literature
| S-EPMC2764355 | biostudies-literature
| S-EPMC7650129 | biostudies-literature
| S-EPMC10916814 | biostudies-literature
| S-EPMC5839297 | biostudies-literature
| S-EPMC4248455 | biostudies-literature
| S-EPMC3775694 | biostudies-literature
| S-EPMC6318108 | biostudies-literature