Ontology highlight
ABSTRACT:
SUBMITTER: Chan JL
PROVIDER: S-EPMC4635915 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Chan Jason L JL Koval Michael J MJ Womelsdorf Thilo T Lomber Stephen G SG Everling Stefan S
Cerebral cortex (New York, N.Y. : 1991) 20140717 12
Cognitive control requires the selection and maintenance of task-relevant stimulus-response associations, or rules. The dorsolateral prefrontal cortex (DLPFC) has been implicated by lesion, functional imaging, and neurophysiological studies to be involved in encoding rules, but the mechanisms by which it modulates other brain areas are poorly understood. Here, the functional relationship of the DLPFC with the superior colliculus (SC) was investigated by bilaterally deactivating the DLPFC while r ...[more]