Ontology highlight
ABSTRACT:
SUBMITTER: Inomata T
PROVIDER: S-EPMC4636218 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Journal of biological methods 20150921 3
Corneal transplantation serves as a reproducible and simple surgical model to study mechanisms regulating immunity and angiogenesis. The simplicity of the model allows for systematic analysis of different mechanisms involved in immune and angiogenic privilege and their failures. This protocol describes how to induce neovessels and inflammation in an actively regulated avascular and immune-privileged site. This involves placing intra-stromal corneal sutures for two weeks, disrupting the privilege ...[more]