Ontology highlight
ABSTRACT:
SUBMITTER: Prill K
PROVIDER: S-EPMC4636364 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Prill Kendal K Windsor Reid Pamela P Wohlgemuth Serene L SL Pilgrim David B DB
PloS one 20151106 11
The vertebrate sarcomere is a complex and highly organized contractile structure whose assembly and function requires the coordination of hundreds of proteins. Proteins require proper folding and incorporation into the sarcomere by assembly factors, and they must also be maintained and replaced due to the constant physical stress of muscle contraction. Zebrafish mutants affecting muscle assembly and maintenance have proven to be an ideal tool for identification and analysis of factors necessary ...[more]