Ontology highlight
ABSTRACT:
SUBMITTER: Turowski VR
PROVIDER: S-EPMC4636843 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Turowski Valeria R VR Aknin Cindy C Maliandi Maria V MV Buchensky Celeste C Leaden Laura L Peralta Diego A DA Busi Maria V MV Araya Alejandro A Gomez-Casati Diego F DF
PloS one 20151030 10
Frataxin plays a key role in eukaryotic cellular iron metabolism, particularly in mitochondrial heme and iron-sulfur (Fe-S) cluster biosynthesis. However, its precise role has yet to be elucidated. In this work, we studied the subcellular localization of Arabidopsis frataxin, AtFH, using confocal microscopy, and found a novel dual localization for this protein. We demonstrate that plant frataxin is targeted to both the mitochondria and the chloroplast, where it may play a role in Fe-S cluster me ...[more]