Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines.
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ABSTRACT:
SUBMITTER: Goyvaerts C
PROVIDER: S-EPMC4637118 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Pros and Cons of Antigen-Presenting Cell Targeted Tumor Vaccines.
Goyvaerts Cleo C Breckpot Karine K
Journal of immunology research 20151025
In therapeutic antitumor vaccination, dendritic cells play the leading role since they decide if, how, when, and where a potent antitumor immune response will take place. Since the disentanglement of the complexity and merit of different antigen-presenting cell subtypes, antitumor immunotherapeutic research started to investigate the potential benefit of targeting these subtypes in situ. This review will discuss which antigen-presenting cell subtypes are at play and how they have been targeted a ...[more]
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