Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC4638289 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Li Jinglong J Zhang Peng P Liu Hongju H Ren Wei W Song Jinjing J Rao Elizabeth E Takahashi Eiki E Zhou Ying Y Li Weidong W Chen Xiaoping X
The Journal of veterinary medical science 20150529 10
Iron is involved in various physiological processes of the human body to maintain normal functions. Abnormal iron accumulation in brain has been reported as a pathogenesis of several neurodegenerative disorders and cognitive impairments. Hemojuvelin (HVJ) is a membrane-bound and soluble protein in mammals that is responsible for the iron overload condition known as juvenile hemochromatosis. Although iron accumulation in brain has been related to neurodegenerative diseases, it remains unknown the ...[more]