Sex differences in DNA methylation assessed by 450 K BeadChip in newborns.
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ABSTRACT:
SUBMITTER: Yousefi P
PROVIDER: S-EPMC4640166 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Publications
Sex differences in DNA methylation assessed by 450 K BeadChip in newborns.
Yousefi Paul P Huen Karen K Davé Veronica V Barcellos Lisa L Eskenazi Brenda B Holland Nina N
BMC genomics 20151109
<h4>Background</h4>DNA methylation is an important epigenetic mark that can potentially link early life exposures to adverse health outcomes later in life. Host factors like sex and age strongly influence biological variation of DNA methylation, but characterization of these relationships is still limited, particularly in young children.<h4>Methods</h4>In a sample of 111 Mexican-American subjects (58 girls , 53 boys), we interrogated DNA methylation differences by sex at birth using the 450 K Be ...[more]
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