Bone-crack detection, targeting, and repair using ion gradients.
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ABSTRACT:
SUBMITTER: Yadav V
PROVIDER: S-EPMC4640360 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
Bone-crack detection, targeting, and repair using ion gradients.
Yadav Vinita V Freedman Jonathan D JD Grinstaff Mark M Sen Ayusman A
Angewandte Chemie (International ed. in English) 20130826 42
Bone cracks can be detected by utilizing the damaged matrix itself as both the trigger and the fuel. A crack in a material with a high mineral content such as bone generates ion gradients, which can be utilized for active targeting and treatment. This approach to targeting a biological structure augments current methods, which are focused on biomacromolecular interactions involving proteins and nucleic acids. ...[more]
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