Ontology highlight
ABSTRACT:
SUBMITTER: Kaneko T
PROVIDER: S-EPMC4640526 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kaneko Takehito T Mashimo Tomoji T
PloS one 20151110 11
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system is a powerful tool for genome editing in animals. Recently, new technology has been developed to genetically modify animals without using highly skilled techniques, such as pronuclear microinjection of endonucleases. Technique for animal knockout system by electroporation (TAKE) method is a simple and effective technology that produces knockout rats by introducing endonuclease mRNAs into intact e ...[more]