Ontology highlight
ABSTRACT:
SUBMITTER: Mattiroli F
PROVIDER: S-EPMC4641499 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Mattiroli Francesca F D'Arcy Sheena S Luger Karolin K
EMBO reports 20151012 11
Histone proteins dynamically regulate chromatin structure and epigenetic signaling to maintain cell homeostasis. These processes require controlled spatial and temporal deposition and eviction of histones by their dedicated chaperones. With the evolution of histone variants, a network of functionally specific histone chaperones has emerged. Molecular details of the determinants of chaperone specificity for different histone variants are only slowly being resolved. A complete understanding of the ...[more]