Ontology highlight
ABSTRACT:
SUBMITTER: Qu H
PROVIDER: S-EPMC4642516 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Qu Huan H Lv Min M Yu Xiang X Lian Xihong X Xu Hui H
Scientific reports 20150813
By structural modification of piperine, some piperine-based phenylsulfonylhydrazone derivatives exhibited an unprecedented and potent narcotic activity against the oriental armyworm, Mythimna separata (Walker). The ND50 values of compounds 6c and 6e against the third-instar larvae of M. separata, which were more potent than those of wilfortrine and wilforgine, were 0.0074 μmol (after 3.5 h), and 0.0075 μmol (after 7 h) per larvae, respectively. By transmission electron microscope, it demonstrate ...[more]