Ontology highlight
ABSTRACT:
SUBMITTER: Vagberg W
PROVIDER: S-EPMC4643221 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20151113
Imaging of muscular structure with cellular or subcellular detail in whole-body animal models is of key importance for understanding muscular disease and assessing interventions. Classical histological methods for high-resolution imaging methods require excision, fixation and staining. Here we show that the three-dimensional muscular structure of unstained whole zebrafish can be imaged with sub-5 μm detail with X-ray phase-contrast tomography. Our method relies on a laboratory propagation-based ...[more]