Ontology highlight
ABSTRACT:
SUBMITTER: Centi AJ
PROVIDER: S-EPMC4643414 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Centi Amanda J AJ Booth Sarah L SL Gundberg Caren M CM Saltzman Edward E Nicklas Barbara B Shea M Kyla MK
Endocrine 20150512 3
Osteocalcin (OC) is a vitamin K-dependent bone protein used as a marker of bone formation. Mouse models have demonstrated a role for the uncarboxylated form of OC (ucOC) in energy metabolism, including energy expenditure and adiposity, but human data are equivocal. The purpose of this study was to determine the associations between changes in measures of OC and changes in body weight and percent body fat in obese, but otherwise healthy post-menopausal women undergoing a 20-week weight loss progr ...[more]