Ontology highlight
ABSTRACT:
SUBMITTER: Ozer HK
PROVIDER: S-EPMC4646028 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Ozer Hatice K HK Dlouhy Adrienne C AC Thornton Jeremy D JD Hu Jingjing J Liu Yilin Y Barycki Joseph J JJ Balk Janneke J Outten Caryn E CE
The Journal of biological chemistry 20150922 46
The sulfhydryl oxidase Erv1 partners with the oxidoreductase Mia40 to import cysteine-rich proteins in the mitochondrial intermembrane space. In Saccharomyces cerevisiae, Erv1 has also been implicated in cytosolic Fe-S protein maturation and iron regulation. To investigate the connection between Erv1/Mia40-dependent mitochondrial protein import and cytosolic Fe-S cluster assembly, we measured Mia40 oxidation and Fe-S enzyme activities in several erv1 and mia40 mutants. Although all the erv1 and ...[more]