Ontology highlight
ABSTRACT:
SUBMITTER: Login FH
PROVIDER: S-EPMC4646276 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
The Journal of biological chemistry 20150903 43
All type III secretion systems (T3SS) harbor a member of the YscU/FlhB family of proteins that is characterized by an auto-proteolytic process that occurs at a conserved cytoplasmic NPTH motif. We have previously demonstrated that YscUCC, the C-terminal peptide generated by auto-proteolysis of Yersinia pseudotuberculosis YscU, is secreted by the T3SS when bacteria are grown in Ca(2+)-depleted medium at 37 °C. Here, we investigated the secretion of this early T3S-substrate and showed that YscUCC ...[more]