Ontology highlight
ABSTRACT:
SUBMITTER: Kowalsky CA
PROVIDER: S-EPMC4646304 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Kowalsky Caitlin A CA Faber Matthew S MS Nath Aritro A Dann Hailey E HE Kelly Vince W VW Liu Li L Shanker Purva P Wagner Ellen K EK Maynard Jennifer A JA Chan Christina C Whitehead Timothy A TA
The Journal of biological chemistry 20150820 44
Knowledge of the fine location of neutralizing and non-neutralizing epitopes on human pathogens affords a better understanding of the structural basis of antibody efficacy, which will expedite rational design of vaccines, prophylactics, and therapeutics. However, full utilization of the wealth of information from single cell techniques and antibody repertoire sequencing awaits the development of a high throughput, inexpensive method to map the conformational epitopes for antibody-antigen interac ...[more]