Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles.
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ABSTRACT:
SUBMITTER: Kang H
PROVIDER: S-EPMC4648690 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
Pharmacokinetics, pharmacodynamics and toxicology of theranostic nanoparticles.
Kang Homan H Mintri Shrutika S Menon Archita Venugopal AV Lee Hea Yeon HY Choi Hak Soo HS Kim Jonghan J
Nanoscale 20151103 45
Nanoparticles (NPs) are considered a promising tool in both diagnosis and therapeutics. Theranostic NPs possess the combined properties of targeted imaging and drug delivery within a single entity. While the categorization of theranostic NPs is based on their structure and composition, the pharmacokinetics of NPs are significantly influenced by the physicochemical properties of theranostic NPs as well as the routes of administration. Consequently, altered pharmacokinetics modify the pharmacodyna ...[more]
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