Ontology highlight
ABSTRACT:
SUBMITTER: Hu HX
PROVIDER: S-EPMC4649674 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Scientific reports 20151118
The one-dimensional pattern of heterocyst in the model cyanobacterium Anabaena sp. PCC 7120 is coordinated by the transcription factor HetR and PatS peptide. Here we report the complex structures of HetR binding to DNA, and its hood domain (HetRHood) binding to a PatS-derived hexapeptide (PatS6) at 2.80 and 2.10 Å, respectively. The intertwined HetR dimer possesses a couple of novel HTH motifs, each of which consists of two canonical α-helices in the DNA-binding domain and an auxiliary α-helix f ...[more]