Ontology highlight
ABSTRACT:
SUBMITTER: Kaushal GS
PROVIDER: S-EPMC4650270 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Kaushal Grace S GS Rognoni Emanuel E Lichtenberger Beate M BM Driskell Ryan R RR Kretzschmar Kai K Hoste Esther E Watt Fiona M FM
The Journal of investigative dermatology 20150819 12
Prominin-1/CD133 (Prom1) is expressed by fibroblasts in the dermal papilla (DP) of the hair follicle (HF). By examining endogenous Prom1 expression and expression of LacZ in the skin of Prom1CreERLacZ (Prom1C-L) mice, in which a CreERT2-IRES-nuclear LacZ cassette is knocked into the first ATG codon of Prom1, we confirmed that Prom1 is expressed in the DP of all developing HFs and also by postnatal anagen follicles. To analyze the fate of Prom1+ DP cells, we crossed Prom1C-L mice with Rosa26-CAG ...[more]