Ontology highlight
ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC4650629 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Wang Chong C Du Wanqing W Su Qian Peter QP Zhu Mingli M Feng Peiyuan P Li Ying Y Zhou Yichen Y Mi Na N Zhu Yueyao Y Jiang Dong D Zhang Senyan S Zhang Zerui Z Sun Yujie Y Yu Li L
Cell research 20150724 10
Mitochondria form networks. Formation of mitochondrial networks is important for maintaining mitochondrial DNA integrity and interchanging mitochondrial material, whereas disruption of the mitochondrial network affects mitochondrial functions. According to the current view, mitochondrial networks are formed by fusion of individual mitochondria. Here, we report a new mechanism for formation of mitochondrial networks through KIF5B-mediated dynamic tubulation of mitochondria. We found that KIF5B pu ...[more]